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“I have prescribed NeilMed’s Sinus Rinse™ for all of my patients that suffer from chronic nasal and sinus problems. The squeeze bottle provides a large volume of buffered saline solution, which is easy to deliver to the nose and thoroughly cleans the nasal passages, providing substantial therapeutic as well as preventive benefit.”
Joseph Jacobs, MD; Professor; Director of Rhinology and Vice-Chair of Otolaryngology, NYU, New York, USA |
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International Archives of Allergy and Immunology |
Garavello W, Somigliana E, Acaia B, Gaini L, Pignataro L, Gaini RM.
Department of Otorhinolaryngology, DNTB, University of Milano-Bicocca, Monza, Italy.
Background: Nasal rinsing appears particularly suitable in the management of pregnant women with seasonal allergic rhinitis since no deleterious effects on the fetus are to be expected. However, to date, no studies have specifically investigated this option. Methods: Pregnant women with seasonal allergic rhinitis were randomized to intranasal lavage with hypertonic saline solution 3 times daily (n = 22) versus no local therapy (n = 23) during a 6-week period corresponding to the pollen season. Patients were invited to keep a daily record of rhinitis symptoms (rhinorrea, obstruction, nasal itching and sneezing), to record consumption of oral antihistamine and to undergo rhinomanometry. Results: The rhinitis score was similar at study entry but a statistically significant improvement in this score was observed in the study group during all subsequent weeks (p < 0.001 for weeks 2-6). The mean number of daily antihistamines use per patient per week was significantly reduced at weeks 2, 3 and 6 (p < 0.001, p < 0.001 and p = 0.001, respectively). Baseline rhinomanometry performed at week 1 showed similar nasal resistance in the study and control groups. In contrast, a statistically significant difference emerged in the 2 following evaluations. At week 3, nasal resistance in the study and control groups was 0.96 ± 0.44 and 1.38 ± 0.52 Pa/ml/s, respectively (p = 0.006). At week 6, it was 0.94 ± 0.38 and 1.35 ± 0.60 Pa/ml/s, respectively (p = 0.006). No adverse effect was reported in the active group. Conclusions: Nasal rinsing is a safe and effective treatment option in pregnant women with seasonal allergic rhinitis.
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Rabago D, Zgierska A.
Department of Family Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI 53715, USA. david.rabago@fammed.wisc.edu
Saline nasal irrigation is an adjunctive therapy for upper respiratory conditions that bathes the nasal cavity with spray or liquid saline. Nasal irrigation with liquid saline is used to manage symptoms associated with chronic rhinosinusitis. Less conclusive evidence supports the use of spray and liquid saline nasal irrigation to manage symptoms of mild to moderate allergic rhinitis and acute upper respiratory tract infections. Consensus guidelines recommend saline nasal irrigation as a treatment for a variety of other conditions, including rhinitis of pregnancy and acute rhinosinusitis. Saline nasal irrigation appears safe, with no reported serious adverse events. Minor adverse effects can be avoided with technique modification and salinity adjustment. |
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Christopher L. Brown and Scott M. Graham
Nasal irrigations are an important component in the management of most sinonasal conditions. Although there is fairly widespread agreement regarding patient benefits, a significant disparity of opinion exists about the effects of irrigations on ciliary beat frequency and mucociliary clearance.
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What to do about sinusitis
If you've ever had a cold that just wouldn't go away, chances are it was sinusitis- an inflammation of the paranasal sinuses, the cavities within the bones that surround the nose.The sinus are lined with a thin membrane that produces mucus, which is normally swept along by hair cells and drains through small openings of the nasal cavity.
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Validation of the Sino-Nasal Outcome Test 20 (SNOT-20)
domains in nonsurgical patients
Melissa A. Pynnonen, M.D., H. Myra Kim, Sc.D. and Jeffrey E. Terrell, M.D.
Subscales identified differences in the impact of two medical interventions on chronic sinonasal symptoms. Reporting
subscale scores might improve the precision of the SNOT-20 instrument, allowing discrimination between various treatments and their
differential impact on sinonasal quality of life.
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Saline irrigation spells relief
for sinusitis sufferers |
Encourage patients with chronic rhinosinusitis to try this simple approach, January 2009 (Vol. 58, No. 1)
Mari Egan, MD, MHPE; John Hickner, MD, MS. Department of Family Medicine, The University of Chicago
Otolaryngologists recommend saline irrigation after sinus surgery to clear secretions, debris, and crusts; reduce the risk of postoperative mucosal adhesions; and expedite mucosal healing. Saline irrigation is also gaining popularity as an alternative approach to chronic sinusitis symptom relief, and several randomized controlled trials (RCTs) have demonstrated both objective and subjective efficacy of this treatment for sinonasal disease. |
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Effects of endoscopic sinus surgery and delivery
device on cadaver sinus irrigation |
Otolaryngology–Head and Neck Surgery (2008) 139, 137-142.ORIGINAL RESEARCH—SINONASAL DISORDERS 
Richard J. Harvey, MD, John C. Goddard, MD, Sarah K. Wise, MD, and
Rodney J. Schlosser, MD, Charleston, SC; and Atlanta, GA
ESS greatly enhances the delivery of nasal
solutions, regardless of delivery device. Pressurized spray solutions
in un-operated sinuses provide little more than nasal cavity
distribution. Use of squeeze bottle/neti pot post-ESS offers a
greatly enhanced ability to deliver solutions to the paranasal sinuses. |
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 Archives of Otolaryngology-Head & Neck Surgery-Nov 2007 |
Nasal Saline for Chronic Sinonasal Symptoms - A Randomized Controlled Trial
Melissa A. Pynnonen, MD; Shraddha S. Mukerji, MD; H. Myra Kim, ScD; Meredith E. Adams, MD; Jeffrey E. Terrell, MD
Nasal irrigations performed with large volume and delivered with low positive pressure (NeilMed Sinus Rinse) are more effective than saline sprays for treatment of chronic nasal and sinus symptoms in a community based population. |
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| Dr. Mehta's Brochure on Saline Irrigation, Allergies and Sinus Disease |
| I am a practicing physician in the field of pulmonary and critical care medicine. I suffered for several years from chronic sinus disease. After being evaluated by an Allergist and Ear, Nose, and Throat specialist, I had corrective surgeries on my sinuses. Of all the treatments tried for controlling and curing my symptoms of sinus disease, the one I found to work the best was a saline nasal rinse. |
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Baby shampoo nasal irrigations |
Baby shampoo nasal irrigations for the symptomatic post–functional endoscopic sinus surgery patient
Alexander G. Chiu, M.D., James N. Palmer, M.D., Bradford A. Woodworth, M.D.,
Laurel Doghramji, R.N., Michael B. Cohen, B.A., Anthony Prince, B.A., and
Noam A. Cohen, M.D., Ph.D.
Baby shampoo nasal irrigation has promise as an inexpensive, tolerable adjuvant to conventional medical therapies for symptomatic patients after FESS. Its greatest benefit may be in improving symptoms of thickened nasal discharge and postnasal drainage.
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Rhinitis and onset of asthma: a longitudinal population-based study |
Rafea Shaaban, Mahmoud Zureik, David Soussan, Catherine Neukirch, Joachim Heinrich, Jordi Sunyer, Matthias Wjst, Isa Cerveri, Isabelle Pin ,
Jean Bousquet, Deborah Jarvis, Peter G Burney, Françoise Neukirch, Bénédicte Leynaert
A close relation between asthma and allergic rhinitis has been reported by several epidemiological and
clinical studies. However, the nature of this relation remains unclear. We used the follow-up data from the European
Community Respiratory Health Survey to investigate the onset of asthma in patients with allergic and non-allergic
rhinitis during an 8·8-year period. |
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Allergic rhinitis: new insights, new therapies |
Dr Paul Carson | 02 April 2008 | Eye, Ear, Nose & Throat
Dr Paul Carson on how his investment in fibre optic technology has provided some new perspectives on allergic rhinitis and the importance of managing the condition At the risk of boring you about a topic many dismiss as trivial, may... |
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| General Medical Literature |
General Medical Literature Review on Saline Nasal Irrigation
Nasal irrigations are often mentioned as adjunctive measures
in treating many sinonasal conditions. Despite their
widespread use, much mystique and uncertainty exist about
the indications and therapeutic mechanisms of nasal
irrigations. Anecdotal evidence and poorly controlled studies
add to the confusion. Recent evidence challenges some of the
assumptions underlying the use of nasal irrigations. |
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Patent Numbers: USA-6,520,384 / 6,669,059 / 6,688,497 Canada-2,443,970 Australia-09/845,759
New Zealand-534041 Mexico-Pa/a/2003/009867. Other patents issued or pending internationally. |
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